品牌:The Native Antigen Company
貨號(hào): DENVX4-VLP-100
品名:Dengue Virus VLP – Serotypes 1-4
Multi-pack of all Dengue Virus VLPs, containing 100ug each of VLPs from serotypes 1-4.
商品詳情參考文獻(xiàn)相關(guān)資料
產(chǎn)品介紹
品牌
The Native Antigen Company
貨號(hào)
DENVX4-VLP-100
品名
Dengue Virus VLP - Serotypes 1-4
規(guī)格
4×100ug
描述
Multi-pack of all Dengue Virus VLPs, containing 100ug each of VLPs from serotypes 1-4
詳情
VLPs are produced in human cell lines using state-of-the-art expression techniques. Constructed from E, M and preM proteins, with secretion from the cell aided by substituting the C terminal 20% with the corresponding Japanese Encephalitis Virus sequence (all internal/transmembrane)
背景
Virus-Like Particles (VLPs) are an emerging vaccine technology. VLPs consist of protein shells comprising outer proteins specific to the virus in question. VLPs are more representative of how viral antigens are presented in vivo and while they are highly immunogenic they are non-infectious as they lack the core genetic material of the virus. Another important advantage of VLPs is that they more effectively activate key aspects of the immune response to achieve potent immune stimulation and to provide immunological memory. VLP-based vaccines have also shown to provide effective protection and are in current use for several diseases and in development for many others